21 CFR 558.455
§ 558.455 Oxytetracycline and neomycin.
United States · 21 CFR — Food and Drugs · Status: effective
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- Citation
- 21 CFR 558.455, § 558.455 Oxytetracycline and neomycin, United States, version 1 as recorded 2026-07-09, yourstate.us, https://yourstate.us/provision/87882
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Full text
(a) Specifications. Type A medicated articles containing oxytetracycline equivalent to 50 grams per pound (g/lb) oxytetracycline hydrochloride and 50 g/lb neomycin sulfate or oxytetracycline equivalent to 100 g/lb oxytetracycline hydrochloride and 100 g/lb neomycin sulfate.
(b) Sponsors. See Nos. 066104 and 069254 in § 510.600(c) of this chapter.
(c) Related tolerances. See §§ 556.430 and 556.500 of this chapter.
(d) Special considerations.
(1) Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. See § 558.6 for additional requirements.
(2) The expiration date of VFDs for oxytetracycline and neomycin medicated feeds must not exceed 6 months from the date of issuance. VFDs for oxytetracycline and neomycin shall not be refilled.
(3) Cattle feeds shall bear the following warning statement: “Use of more than one product containing neomycin or failure to follow withdrawal times may result in illegal drug residues.”
(e) Indications for use—(1) Chickens. It is used in feed as follows:
(2) Turkeys. It is used in feed as follows:
(3) Swine. It is used in feed as follows:
(4) Cattle. It is used in feed as follows:
(5) Sheep. It is used in feed as follows:
(ii) [Reserved]
Legislative history
This is a federal regulation, adopted through agency rulemaking under the Administrative Procedure Act — not enacted by a recorded vote of Congress.