§ 1308.11 Schedule I.

(a) Schedule I shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section. Each drug or substance has been assigned the DEA Controlled Substances Code Number set forth opposite it. (b) Opiates. Unless specifically excepted or unless listed in another schedule, any of the following opiates, including their isomers, esters, ethers, salts, and salts of isomers, esters and ethers, whenever the existence of such isomers, esters, ethers and salts is possible within the specific chemical designation (for purposes of 3-methylthiofentanyl only, the term isomer includes the optical and geometric isomers): (c) Opium derivatives. Unless specifically excepted or unless listed in another schedule, any of the following opium derivatives, its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation: (d) Hallucinogenic substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation, which contains any quantity of the following hallucinogenic substances, or which contains any of its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation (for purposes of this paragraph only, the term “isomer” includes the optical, position and geometric isomers): (e) Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a depressant effect on the central nervous system, including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation: (f) Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers, and salts of isomers: (g) Cannabimimetic agents. Unless specifically exempted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of cannabimimetic agents, or which contains their salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation: (h) Temporary listing of substances subject to emergency scheduling. Any material, compound, mixture or preparation which contains any quantity of the following substances: (i) Fentanyl-related substance means any substance not otherwise listed under another Administration Controlled Substance Code Number, and for which no exemption or approval is in effect under section 505 of the Federal Food, Drug, and Cosmetic Act [21 U.S.C. 355], that is structurally related to fentanyl by one or more of the following modifications: (A) Replacement of the phenyl portion of the phenethyl group by any monocycle, whether or not further substituted in or on the monocycle; (B) Substitution in or on the phenethyl group with alkyl, alkenyl, alkoxyl, hydroxyl, halo, haloalkyl, amino or nitro groups; (C) Substitution in or on the piperidine ring with alkyl, alkenyl, alkoxyl, ester, ether, hydroxyl, halo, haloalkyl, amino or nitro groups; (D) Replacement of the aniline ring with any aromatic monocycle whether or not further substituted in or on the aromatic monocycle; and/or (E) Replacement of the N-propionyl group by another acyl group. (ii) This definition includes, but is not limited to, the following substances: (A)-(B) [Reserved] 1.At 83 FR 5191, Feb. 6, 2018, § 1308.11 was amended by adding paragraph (h)(30), effective Feb. 6, 2018, through Feb. 6, 2020. Effective Feb. 6, 2020, Congress extended the effective period for paragraph (h)(30) until May 6, 2021, by Public Law 116-114. Effective May 4, 2021, Congress extended the effective period for paragraph (h)(30) until October 22, 2021, by Public Law 117-12. Effective Sept. 30, 2021, Congress extended the effective period for paragraph (h)(30) until Jan. 28, 2022, by Public Law 117-43. Effective Jan. 13, 2022, Congress extended the effective period for paragraph (h)(30) until Feb. 18, 2022, by Public Law 117-70. Effective Feb. 18, 2022, Congress extended the effective period for paragraph (h)(30) until Mar. 11, 2022, by Public Law 117-86. Effective Mar. 11, 2022, Congress extended the effective period for paragraph (h)(30) until Mar. 15, 2022 by Public Law 117-95. Effective Mar. 15, 2022, Congress extended the effective period for paragraph (h)(30) until Dec. 31, 2022 by Public Law No. 117-103. Effective Dec. 29, 2022, Congress extended the effective period for paragraph (h)(30) until Dec. 31, 2024 by Public Law No. 117-328. Congress extended the effective period for paragraph (h)(30) until Mar. 31, 2025 by Public Law No. 116-114. Congress extended the effective period for (h)(30) until Sept. 30, 2025 by Public Law No. 119-4. 2. At 88 FR 86045, Dec. 12, 2023, § 1308.11 was amended by adding paragraphs (h)(62) through (h)(67), effective Dec. 12, 2023 through Dec. 12, 2025. At 90 FR 57356 and 57542, Dec. 11, 2025, paragraphs (h)(62) and (65) were extended through Dec. 12, 2026. At 91 FR 21963, Apr. 24, 2026, (h)(62) was removed. 3. At 90 FR 48265, Oct. 15, 2025, § 1308.11 was amended by adding paragraphs (h)(79) through (85), effective Oct. 15, 2025, until Oct. 15, 2027. 4. At 91 FR 12508, Mar. 16, 2026, § 1308.11 was amended by adding paragraph (h)(86), effective from Mar. 16, 2026, until Mar. 16, 2028. 5. At 91 FR 30209, May 22, 2026, § 1308.11 was amended by adding paragraph (h)(87), effective May 22, 2026 through May 22, 2028.